| Joe Mixon | RB | Yes | Probable | Knee | Mixon was confined to a limited role in practice due to a knee injury but is expected to suit up for Sunday's contest against the Ravens. |
| John Ross | WR | Yes | Questionable | Groin | Ross has a groin injury and it is unclear if he will play Sunday against the Ravens. |
| A.J. Green | WR | Yes | Doubtful | Toe | Green sustained a toe injury on his right foot and it is unlikely he will suit up for Sunday's clash against the Ravens. |
| Alex Redmond | OL | Yes | Questionable | Hamstring | Redmond missed the last game hobbled by a hamstring injury, leaving his status clouded for Sunday's contest against the Ravens. |
| Nick Vigil | LB | Yes | Out | Knee | Vigil sustained a sprained MCL in his knee and will not return to the field Sunday against the Ravens. |
| Preston Brown | LB | Yes | Out | Knee | Brown is dealing with a leg injury and will not suit up against the Ravens on Sunday. |
| Darqueze Dennard | DB | Yes | Questionable | Shoulder | Dennard has sat out the previous three games with a shoulder injury and it is uncertain if he will play Sunday against the Ravens. |
| Dre Kirkpatrick | DB | Yes | Questionable | Concussion | Kirkpatrick has been entered into the league's concussion protocol and it unknown if he will be cleared in time for Sunday's contest against Ravens. |
| Josh Malone | WR | No | Out | Hamstring | Malone missed the last game dealing with a hamstring injury and will not be available for Sunday's matchup against the Ravens. |
| Tyler Eifert | TE | No | Out | Ankle | Eifert is recovering from surgery to repair a broken right ankle while on the injured reserve list. |
| Mason Schreck | TE | No | Out | Knee | Schreck is on injured reserve due to a knee injury. |
| Tyler Kroft | TE | No | Out | Foot | Kroft is on the injured reserve list recovering from surgery to repair a fractured foot. |
| Cethan Carter | TE | No | Out | Arm | Carter suffered a shoulder injury and is on the injured reserve list and it has yet to be established if he will return for Sunday's matchup against the Ravens. |
| Rod Taylor | OL | No | Out | Knee | Taylor has landed on injured reserve with a torn ACL. |
| Adolphus Washington | DL | No | Out | Knee | Washington is tending to a knee injury and will not be active Sunday against the Ravens. |
| Ryan Glasgow | DL | No | Out | Knee | Glasgow is on the injured reserve list with a torn ACL. |
| Carl Lawson | DL | No | Out | Knee | Lawson suffered a torn ACL in his knee and is on the injured reserve list. |
| Vontaze Burfict | LB | No | Questionable | Hip | Burfict has sat out the last two games due to a left hip injury but is expected to line up against the Ravens on Sunday, provided no setbacks occur. |
| Vincent Rey | LB | No | Questionable | Groin | Rey is bothered by a groin injury and it is uncertain if it will hinder his availability against the Ravens on Sunday. |
| Davontae Harris | DB | No | Out | Knee | Harris has been activated from injured reserve after recovering from a knee sprain. It is unknown if he will suit up for Sunday's contest against the Ravens. |
| Trayvon Henderson | DB | No | Out | Knee | Henderson is on the injured reserve list with an arm injury. |
