| Tyron Smith | OL | Yes | Questionable | Back | Smith is dealing with a back spasms and it is unknown if he will suit up against the Falcons on Sunday. |
| Zack Martin | OL | Yes | Questionable | Knee | Martin has a knee injury and it is unclear if he will play Sunday against the Falcons. |
| Maliek Collins | DL | Yes | Questionable | Knee | Collins was removed from the last game due to a knee injury and it has yet to be established if he will be active for Sunday's contest against the Falcons. |
| Antwaun Woods | DL | Yes | Doubtful | Concussion | Woods has been diagnosed with a concussion and it is unlikely he will be cleared in time for Sunday's clash against the Falcons. |
| Jameill Showers | QB | No | Out | Knee | Showers is on injured reserve due to a torn ACL. |
| Cedrick Wilson | WR | No | Out | Shoulder | Wilson is on the injured reserve list due to a torn labrum in his shoulder and it is unclear if he will be activated in time for Sunday's contest against the Falcons. |
| Terrance Williams | WR | No | Out | Foot | Williams is on injured reserve while recovering from surgery to repair a right foot injury and it is uncertain if he will return Week 13 against the Saints. |
| Tavon Austin | WR | No | Out | Groin | Austin has sat out the previous three games due to a groin strain and will not return to the field Sunday against the Falcons. |
| Dustin Stanton | OL | No | Out | Undisclosed | |
| Connor Williams | OL | No | Questionable | Knee | Williams sat out the previous game due to a knee injury and it is undetermined if he will be available against the Falcons on Sunday. |
| Parker Ehinger | OL | No | Out | Knee | Ehinger is on injured reserve with a knee injury and it has yet to be determined if he will be activated against the Falcons on Sunday. |
| Travis Frederick | OL | No | Out | Illness | Frederick in on the injured reserve list as he has been diagnosed with a condition known as Guillain Barre Syndrome that impacts the autoimmune system. It is unknown if he will be activated in Week 15 against the Colts. |
| Marcus Martin | OL | No | Out | Toe | Martin has been designated for the injured reserve list due to a ligament tear in his right big toe. |
| David Irving | DL | No | Out | Ankle | Irving has a high-ankle sprain and is expected to miss four-to-six weeks. |
| Datone Jones | DL | No | Out | Hamstring | Jones has landed on the injured reserve list due to a hamstring injury. |
| Taco Charlton | DL | No | Out | Shoulder | Charlton missed the last game due to a shoulder injury and will not face the Falcons on Sunday. |
| Daniel Ross | DL | No | Out | Calf | Ross exited the previous game due to a calf strain and will not suit up for Sunday's contest against the Falcons. |
| Sean Lee | LB | No | Out | Hamstring | Lee suffered a hamstring injury and is expected to need four-to-six weeks to heal. |
| Joe Thomas | LB | No | Questionable | Foot | Thomas has missed the past four games with a foot injury and it is unclear if he will return against the Falcons on Sunday. |
| Marqueston Huff | DB | No | Out | Undisclosed | |
| C.J. Goodwin | DB | No | Out | Forearm | Goodwin has landed on the injured reserve as he recovers from surgery to repair a fractured forearm. |
